UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F COVER PAGE
OMB APPROVAL
OMB Number:3235-0006
Expires:July 31, 2015
Estimated average burden
hours per response:23.8
Report for the Calendar Year or Quarter Ended:
09-30-2019
Check here if Amendment: ☐ Amendment Number:
This Amendment (Check only one.):☐ is a restatement.
☐ adds new holdings entries.

Institutional Investment Manager Filing this Report:

Name:
Asymmetry Capital Management, L.P.
Address:
101 CALIFORNIA STREET
SUITE 1725
SAN FRANCISCO, CA 94111
Form 13F File Number:
028-17016

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.


Person Signing this Report on Behalf of Reporting Manager:
Name:
Cynthia Goldsmith
Title:
CFO
Phone:
4158014604


Signature, Place, and Date of Signing:

Cynthia Goldsmith
                         [Signature]
San Francisco, CALIFORNIA
                 [City, State]
11-12-2019
                           [Date]
                          

Report Type (Check only one.):

☒ 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.) 

☐ 13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).) 

☐ 13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)


Form 13F Summary Page

Report Summary:

Number of Other Included Managers:
0
Form 13F Information table Entry Total:
22
Form 13F Information table Value Total:
46651
          (thousands)

List of Other Included Managers:

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.
[If there are no entries in this list, state "NONE" and omit the column headings and list entries.]

  
NONE


UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number:3235-0006
Expires:July 31, 2015
Estimated average burden
hours per response:23.8
COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ACCELERON PHARMA INCCOM00434H1081,87547,453SHSOLE47,453 0 0
AMARIN CORP PLC -ADRADR0231112061,584104,509SHSOLE104,509 0 0
ARENA PHARMACEUTICALS INCCOM04004760774516,272SHSOLE16,272 0 0
ANTARES PHARMA INCCOM0366421061,262377,399SHSOLE377,399 0 0
BIO-RAD LABORATORIES-ACOM0905722071,8765,638SHSOLE5,638 0 0
BIOMARIN PHARMACEUTICAL INCCOM09061G1013,32049,262SHSOLE49,262 0 0
CRISPR THERAPEUTICS AGCOMH171821081,52237,141SHSOLE37,141 0 0
DEXCOM INCCOM2521311072,20414,770SHSOLE14,770 0 0
GLOBAL BLOOD THERAPEUTICS INCCOM37890U1083,64075,011SHSOLE75,011 0 0
GILEAD SCIENCES INCCOM3755581033,39053,486SHSOLE53,486 0 0
GW PHARMACEUTICALS -ADRADR36197T1032,73023,729SHSOLE23,729 0 0
HERON THERAPEUTICS INCCOM42774610272739,273SHSOLE39,273 0 0
INSMED INCCOM4576693074,420250,584SHSOLE250,584 0 0
MYOKARDIA INCCOM62857M1052,49847,902SHSOLE47,902 0 0
NATERA INCCOM6323071042,07063,112SHSOLE63,112 0 0
NUCANA PLC-ADRADR67022C1061,190164,366SHSOLE164,366 0 0
PENUMBRA INCCOM70975L1073632,700SHSOLE2,700 0 0
PORTOLA PHARMACEUTICALS INCCOM7370101084,031150,299SHSOLE150,299 0 0
PTC THERAPEUTICSCOM69366J2004,074120,449SHSOLE120,449 0 0
TANDEM DIABETES CARE INCCOM8753722031,12018,995SHSOLE18,995 0 0
TWIST BIOSCIENCE CORPCOM90184D10091338,218SHSOLE38,218 0 0
VERRICA PHARMACEUTICALS INCCOM92511W1081,09774,301SHSOLE74,301 0 0