|
NAME OF SUBSIDIARY
|
STATE OR OTHER
JURISDICTION OF
INCORPORATION OR
ORGANIZATION
|
|
|
ICON Global Treasury Unlimited Company
|
Ireland
|
|
|
ICON Clinical Research Limited
|
Ireland
|
|
|
ICON Holdings Unlimited Company
|
Ireland
|
|
|
DOCS Resourcing Limited
|
Ireland
|
|
|
ICON Clinical International Unlimited Company
|
Ireland
|
|
|
ICON Clinical Research Property Development (Ireland) Limited
|
Ireland
|
|
|
Accellacare Limited
|
Ireland
|
|
|
ICON Operational Holdings Unlimited Company
|
Ireland
|
|
|
ICON Operational Financing Unlimited Company
|
Ireland
|
|
|
ICON Investments Four Unlimited Company
|
Ireland
|
|
|
ICON Clinical Global Holdings Unlimited Company
|
Ireland
|
|
|
ICON Luxembourg S.à r.l.
|
Luxembourg
|
|
|
ICON Early Phase Services, LLC
|
Texas
|
|
|
Beacon Bioscience, Inc.
|
Delaware
|
|
|
ICON Clinical Research LLC
|
Delaware
|
|
|
ICON Laboratory Services, Inc.
|
Delaware
|
|
|
MolecularMD Corp.
|
Delaware
|
|
|
ICON US Holdings Inc.
|
Delaware
|
|
|
PriceSpective LLC
|
Delaware
|
|
|
DOCS Global, Inc.
|
New Jersey
|
|
|
Accellacare US Inc.
|
North Carolina
|
|
|
Clinical Resource Network, LLC
|
Illinois
|
|
|
ICON Clinical Investments LLC
|
Delaware
|
|
|
PRA Health Sciences, Inc.
|
Delaware
|
|
|
ReSearch Pharmaceutical Services, Inc.
|
Delaware
|
|
|
Source Healthcare Analytics, LLC
|
Delaware
|
|
|
Symphony Health Solutions Corporation
|
Delaware
|
|
|
Pharmaceutical Research Associates, Inc.
|
Virginia
|
|
|
PRA Holdings, Inc.
|
Delaware
|
|
|
PRA International, LLC
|
Delaware
|
|
|
RPS Global Holdings, LLC
|
Delaware
|
|
|
RPS Parent Holding LLC
|
Delaware
|
|
|
Roy RPS Holdings LLC
|
Delaware
|
|
|
CRN Holdings, LLC
|
Delaware
|
|
NAME (STATE OR OTHER JURISDICTION OF INCORPORATION OR ORGANIZATION)
|
OWNER
|
PERCENT PLEDGED
|
||
|
ICON Investments Six Designated Activity Company (Ireland)
|
ICON plc
|
100%
|
||
|
ICON Clinical Research Limited (Ireland)
|
ICON Operational Holdings Unlimited Company
|
100%
|
||
|
ICON Holdings Unlimited Company (Ireland)
|
ICON Operational Financing Unlimited Company
|
100%
|
||
|
ICON Investments Four Unlimited Company (Ireland)
|
ICON Clinical Global Holdings Unlimited Company
|
100%
|
||
|
ICON Operational Holdings Unlimited Company (Ireland)
|
ICON Operational Financing Unlimited Company
|
100%
|
||
|
ICON Operational Financing Unlimited Company (Ireland)
|
ICON Clinical Global Holdings Unlimited Company
|
100%
|
||
|
ICON Clinical Global Holdings Unlimited Company (Ireland)
|
ICON plc
|
100%
|
||
|
ICON Investments Five Unlimited Company (Ireland)
|
ICON plc
|
100%
|
||
|
DOCS Resourcing Limited (Ireland)
|
ICON Clinical International Unlimited Company
|
100%
|
||
|
ICON Clinical International Unlimited Company (Ireland)
|
ICON Holdings Unlimited Company
|
100%
|
||
|
ICON Clinical International Unlimited Company (Ireland)
|
ICON plc
|
100%
|
||
|
ICON Clinical Research Property Holdings (Ireland) Limited (Ireland)
|
ICON plc
|
100%
|
||
|
ICON (LR) Limited (United Kingdom)
|
ICON Clinical Research Limited
|
100%
|
||
|
ICON Holdings Clinical Research International Limited (Ireland)
|
ICON Holdings Unlimited Company
|
100%
|
||
|
Accellacare Limited (Ireland)
|
ICON Holdings Unlimited Company
|
100%
|
||
|
ICON Global Treasury Unlimited Company (Ireland)
|
ICON Clinical Research Limited
|
100%
|
||
|
ICON Global Treasury Unlimited Company (Ireland)
|
ICON plc
|
100%
|
||
|
ICON Luxembourg S.à r.l.(Luxembourg)
|
ICON Holdings Unlimited Company
|
100%
|
||
|
ICON Luxembourg S.à r.l. (Luxembourg)
|
ICON Clinical Research Limited
|
100%
|
||
|
ICON Luxembourg S.à r.l. (Luxembourg)
|
ICON plc
|
100%
|
||
|
ICON Early Phase Services, LLC (f/k/a Healthcare Discoveries, LLC) (Texas)
|
ICON Clinical Research LLC
|
100%
|
||
|
Beacon Bioscience, Inc. (Delaware)
|
ICON Clinical Research LLC
|
100%
|
||
|
ICON Clinical Research LLC (Delaware)
|
ICON US Holdings Inc.
|
100%
|
||
|
ICON Laboratory Services, Inc. (f/k/a ICON Central Laboratories, Inc.) (Delaware)
|
ICON US Holdings Inc.
|
100%
|
||
|
MolecularMD Corp. (Delaware)
|
ICON Laboratory Services, Inc. (f/k/a ICON Central Laboratories, Inc.)
|
100%
|
||
|
ICON US Holdings Inc. (Delaware)
|
ICON Operational Financing Unlimited Company
|
100%
|
||
|
PriceSpective LLC (Delaware)
|
ICON Clinical Research LLC
|
100%
|
||
|
CRN Holdings, LLC (Delaware)
|
ICON Clinical Research LLC
|
100%
|
||
|
ICON Clinical Investments, LLC (Delaware)
|
ICON Luxembourg S.à r.l
|
100%
|
||
|
Clinical Resource Network, LLC (d/b/a Symphony Clinical Research) (Illinois)
|
CRN Holdings, LLC
|
100%
|
||
|
DOCS Global, Inc. (New Jersey)
|
ICON Clinical Research LLC
|
100%
|
||
|
Accellacare US Inc. (North Carolina)
|
ICON Clinical Research LLC
|
100%
|
||
|
RPS Bermuda, Ltd. (Bermuda)
|
ReSearch Pharmaceutical Services, Inc.
|
65%
|
||
|
Services de Recherche Pharmaceutique Srl (Canada)
|
ReSearch Pharmaceutical Services, Inc.
|
65%
|
|
PRA Health Sciences Colombia Ltda. (Colombia)
|
Pharmaceutical Research Associates, Inc.
|
65%
|
||
|
Pharmaceutical Research Associates Hungary Research and Development Ltd. (Hungary)
|
Pharmaceutical Research Associates, Inc.
|
65%
|
||
|
Pharmaceutical Research Associates Italy S.r.l. (Italy)
|
Pharmaceutical Research Associates, Inc.
|
65%
|
||
|
Pharmaceutical Research Associates Mexico S. de R.L. de C. V. (Mexico)
|
Pharmaceutical Research Associates, Inc.
|
65%
|
||
|
Pharmaceutical Research Associates Mexico S. de R.L. de C. V. (Mexico)
|
PRA International, LLC
|
65%
|
||
|
ReSearch Pharmaceutical Services Netherlands B.V. (Netherlands)
|
ReSearch Pharmaceutical Services, Inc.
|
65%
|
||
|
RPS Perú S.A.C. (Peru)
|
Pharmaceutical Research Associates, Inc.
|
65%
|
||
|
Research Pharmaceutical Services Puerto Rico, Inc. (Puerto Rico)
|
ReSearch Pharmaceutical Services, Inc.
|
65%
|
||
|
Pharmaceutical Research Associates Romania S.R.L. (Romania)
|
Pharmaceutical Research Associates, Inc.
|
65%
|
||
|
Pharmaceutical Research Associates España, S.A.U. (Spain)
|
Pharmaceutical Research Associates, Inc.
|
65%
|
||
|
PRA International Sweden AB (Sweden)
|
Pharmaceutical Research Associates, Inc.
|
65%
|
||
|
RPS Research (Thailand) Co., Ltd. (Thailand)
|
ReSearch Pharmaceutical Services, Inc.
|
65%
|
||
|
Sterling Synergy Systems Limited (United Kingdom)
|
Pharmaceutical Research Associates, Inc.
|
65%
|
||
|
ClinStar LLC (California)
|
Pharmaceutical Research Associates, Inc.
|
100%
|
||
|
Nextrials, Inc. (California)
|
Pharmaceutical Research Associates, Inc.
|
100%
|
||
|
Care Innovations, Inc. (Delaware)
|
Pharmaceutical Research Associates, Inc.
|
100%
|
||
|
CRI NewCo, Inc. (Delaware)
|
Pharmaceutical Research Associates, Inc.
|
100%
|
||
|
International Medical Technical Consultants, LLC (Delaware)
|
Pharmaceutical Research Associates, Inc.
|
100%
|
||
|
Parallel 6, Inc. (Delaware)
|
Pharmaceutical Research Associates, Inc.
|
100%
|
||
|
PRA Early Development Research, Inc. (f/k/a Pharma Bio-Research USA, Inc.) (Delaware)
|
Pharmaceutical Research Associates, Inc.
|
100%
|
||
|
PRA Health Sciences, Inc. (Delaware)
|
ICON US Holdings Inc.
|
100%
|
||
|
PRA Holdings, Inc. (Delaware)
|
PRA Health Sciences, Inc.
|
100%
|
||
|
PRA Receivables, LLC (Delaware)
|
Pharmaceutical Research Associates, Inc.
|
100%
|
||
|
ReSearch Pharmaceutical Services, Inc. (Delaware)
|
Roy RPS Holdings, LLC
|
100%
|
||
|
ReSearch Pharmaceutical Services, LLC (Delaware)
|
ReSearch Pharmaceutical Services, Inc.
|
100%
|
||
|
Source Healthcare Analytics, LLC (Delaware)
|
Symphony Health Solutions Corporation
|
100%
|
||
|
Sunset Hills, LLC (Delaware)
|
Pharmaceutical Research Associates, Inc.
|
100%
|
||
|
Symphony Health Solutions Corporation (Delaware)
|
Pharmaceutical Research Associates, Inc.
|
100%
|
||
|
Pharmaceutical Research Associates, Inc. (Virginia)
|
PRA International, LLC
|
100%
|
||
|
PRA International, LLC (Delaware)
|
PRA Holdings, Inc.
|
100%
|
||
|
Roy RPS Holdings LLC (Delaware)
|
RPS Parent Holding LLC
|
100%
|
||
|
RPS Global Holdings, LLC (Delaware)
|
PRA Holdings, Inc.
|
100%
|
||
|
RPS Parent Holding LLC (Delaware)
|
RPS Global Holdings, LLC
|
100%
|
||
|
ICON Government and Public Health Solutions, Inc. (Virginia)
|
ICON US Holdings Inc.
|
100%
|
||
|
Accellacare of Bristol, LLC (Tennessee)
|
Accellacare US Inc.
|
100%
|
||
|
Accellacare of Charleston, LLC (South Carolina)
|
Accellacare US Inc.
|
100%
|
||
|
Accellacare of Charlotte, LLC (North Carolina)
|
Accellacare US Inc.
|
100%
|
||
|
Accellacare of Christie Clinic, LLC (Illinois)
|
Accellacare US Inc.
|
100%
|
||
|
Accellacare of Hickory, LLC (North Carolina)
|
Accellacare US Inc.
|
100%
|
||
|
Accellacare of Raleigh, LLC (North Carolina)
|
Accellacare US Inc.
|
100%
|
||
|
Accellacare of Rocky Mount, LLC (North Carolina)
|
Accellacare US Inc.
|
100%
|
||
|
Accellacare of Salisbury, LLC (North Carolina)
|
Accellacare US Inc.
|
100%
|
||
|
Accellacare of Wilmington, LLC (North Carolina)
|
Accellacare US Inc.
|
100%
|
||
|
Accellacare of Winston-Salem, LLC (North Carolina)
|
Accellacare US Inc.
|
100%
|
||
|
Averion Europe GmbH (Germany)
|
ICON Clinical Research LLC
|
65%
|
||
|
CHC Group, LLC (Delaware)
|
ICON Clinical Research LLC
|
100%
|
||
|
PubsHub LLC (Delaware)
|
ICON Clinical Research LLC
|
100%
|
||
|
Global Pharmaceutical Strategies Group, LLC (Delaware)
|
ICON Clinical Research LLC
|
100%
|
||
|
MMMM Group, LLC (Delaware)
|
ICON Clinical Research LLC
|
100%
|
||
|
ICON Tennessee, LLC (Delaware)
|
ICON Clinical Research LLC
|
100%
|
||
|
ADDPLAN, Inc. (Delaware)
|
ICON Clinical Research LLC
|
100%
|
||
|
ICON Clinical Research LP (Delaware)
|
ICON Clinical Research LLC
|
100%
|
||
|
ICON Clinical Research LP (Delaware)
|
ICON Tennessee, LLC
|
100%
|
||
|
CRN North America, LLC (d/b/a Symphony Clinical Staffing) (Delaware)
|
CRN Holdings, LLC
|
100%
|
||
|
Symphony Clinical Research Sp. Z O O. (Poland)
|
CRN Holdings, LLC
|
65%
|
||
|
ICON Clinical Research Holdings (U.K.) Limited (United Kingdom)
|
Pharmaceutical Research Associates, Inc.
|
65%
|
||
|
Oncacare Limited (Ireland)
|
ICON Clinical Research Limited
|
100%
|
||
|
Biotel Research LLC (Delaware)
|
ICON US Holdings Inc.
|
100%
|
||
|
HumanFirst Inc. (Delaware)
|
ICON US Holdings Inc.
|
100%
|
||
|
ICON Clinical Research Holdings (Ireland) Unlimited Company (Ireland)
|
ICON Holdings Unlimited Company
|
100%
|