UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F COVER PAGE
OMB APPROVAL
OMB Number:3235-0006
Expires:July 31, 2015
Estimated average burden
hours per response:23.8

Report for the Calendar Year or Quarter Ended:
03-31-2020
Check here if Amendment: Amendment Number:
This Amendment (Check only one.): is a restatement.
adds new holdings entries.

Institutional Investment Manager Filing this Report:

Name:
INTERNATIONAL BIOTECHNOLOGY TRUST PLC
Address:
10 HAREWOOD AVENUE
LONDON, X0 NW1 6AA
Form 13F File Number:

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.


Person Signing this Report on Behalf of Reporting Manager:
Name:
James Costine
Title:
Authorised Signatory
Phone:
0044 2074217081


Signature, Place, and Date of Signing:

James Costine
                         [Signature]
London, UNITED KINGDOM
                 [City, State]
05-12-2020
                           [Date]
                          

Report Type (Check only one.):

13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.) 

13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).) 

13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)


Form 13F Summary Page

Report Summary:

Number of Other Included Managers:
0
Form 13F Information table Entry Total:
57
Form 13F Information table Value Total:
219373
          (thousands)

List of Other Included Managers:

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.
[If there are no entries in this list, state "NONE" and omit the column headings and list entries.]

  
NONE


UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number:3235-0006
Expires:July 31, 2015
Estimated average burden
hours per response:23.8

COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ACADIA PHARMACEUTICALS INCCOM00422510814,232337,000SHSOLE337,000 0 0
ACCELERON PHARMA INCCOM00434H1081,61718,000SHSOLE18,000 0 0
Agios Pharmaceuticals IncCOM00847X10476221,500SHSOLE21,500 0 0
Alexion Pharmaceuticals IncCOM0153511096,61173,641SHSOLE73,641 0 0
ALKERMES PLCSHSG0176710574952,000SHSOLE52,000 0 0
ALLAKOS INCCOM01671P10069215,700SHSOLE15,700 0 0
Alnylam Pharmaceuticals IncCOM02043Q1072,42522,300SHSOLE22,300 0 0
Amarin Corp PlcSPONS ADR NEW0231112061,274320,000SHSOLE320,000 0 0
Amgen IncCOM03116210013,38066,000SHSOLE66,000 0 0
Amicus Therapeutics IncCOM03152W10987394,600SHSOLE94,600 0 0
ANAPTYSBIO INCCOM03272410614010,000SHSOLE10,000 0 0
Arena Pharmaceuticals IncCOM04004760769016,500SHSOLE16,500 0 0
Ascendis Pharma ASSponsored ADR04351P1011,54813,800SHSOLE13,800 0 0
Biogen IncCOM09062X10314,45845,700SHSOLE45,700 0 0
Biomarin Pharmaceutical IncCOM09061G10114,338169,784SHSOLE169,784 0 0
Bluebird Bio IncCOM09609G10050511,000SHSOLE11,000 0 0
Blueprint Medicines CorpCOM09627Y10970012,000SHSOLE12,000 0 0
CRISPR THERAPEUTICS AGNAMEN AKTH1718210893022,000SHSOLE22,000 0 0
CHEMOCENTRYX INCCOM16383L1067,629190,000SHSOLE190,000 0 0
DECIPHERA PHARMACEUTICALS INCCOM24344T10169717,000SHSOLE17,000 0 0
LILLY ELI & COCOM5324571082,77020,000SHSOLE20,000 0 0
ENANTA PHARMACEUTICALS INCCOM29251M1062,38546,500SHSOLE46,500 0 0
ESPERION THERAPEUTICS INC NECOM29664W1052989,500SHSOLE9,500 0 0
Exact Sciences CorpCOM30063P10561910,700SHSOLE10,700 0 0
Exelixis IncCOM30161Q1041,776103,534SHSOLE103,534 0 0
FibroGen IncCOM31572Q80868419,700SHSOLE19,700 0 0
GW Pharmaceuticals PlcADS36197T10389310,200SHSOLE10,200 0 0
Gilead Sciences IncCOM37555810317,718237,284SHSOLE237,284 0 0
Global Blood TherapeuticsCOM37890U1084989,800SHSOLE9,800 0 0
Halozyme Therapeutics IncCOM40637H1095,531307,633SHSOLE307,633 0 0
HORIZON THERAPEUTICS PUB LTDSHSG4618810111,662394,000SHSOLE394,000 0 0
IMMUNOMEDICS INCCOM45290710897072,000SHSOLE72,000 0 0
Incyte CorpCOM45337C1027,28699,500SHSOLE99,500 0 0
INSMED INCCOM45766930753733,600SHSOLE33,600 0 0
INTRA CELLULAR THERAPIES INCCOM46116X10135223,000SHSOLE23,000 0 0
Ionis Pharmaceuticals IncCOM4622221002,54353,781SHSOLE53,781 0 0
Kalvista Pharmaceuticals IncCOM48349710338150,000SHSOLE50,000 0 0
Kalvista Pharmaceuticals IncCOM4834971031,350177,433SHSOLE177,433 0 0
MERCK & CO INCCOM58933Y1056,40383,200SHSOLE83,200 0 0
Millendo Therapeutics IncCOM60040X103939177,825SHSOLE177,825 0 0
MIRATI THERAPEUTICS INCCOM60468T1053,37443,900SHSOLE43,900 0 0
MOMENTA PHARMACEUTICALS INCCOM60877T10073427,000SHSOLE27,000 0 0
Myokardia INCCOM62857M10574315,859SHSOLE15,859 0 0
NEKTAR THERAPEUTICSCOM6402681081,19367,000SHSOLE67,000 0 0
Neurocrine Biosciences IncCOM64125C1099,288107,300SHSOLE107,300 0 0
PTC Therapuetics COMCOM69366J20011,971269,000SHSOLE269,000 0 0
PRINCIPIA BIOPHARMA INCCOM74257L1081,35123,100SHSOLE23,100 0 0
Sage Therapeutics IncCOM78667J1081,07737,600SHSOLE37,600 0 0
Sarepta Therapeutics IncCOM8036071002,74428,100SHSOLE28,100 0 0
Seattle Genetics IncCOM8125781026,55756,900SHSOLE56,900 0 0
SUTRO BIOPHARMA INCCOM8693671021,375139,331SHSOLE139,331 0 0
Tricida IncCOM89610F10163529,000SHSOLE29,000 0 0
TURNING POINT THERAPEUTICS ICOM90041T1081,54235,000SHSOLE35,000 0 0
UNIQURE NVSHSN900641011,28927,500SHSOLE27,500 0 0
Vertex Pharmaceuticals IncCOM92532F10018,51777,822SHSOLE77,822 0 0
ZEALAND PHARMA A SSPONSORED ADR98920Y3041835,653SHSOLE5,653 0 0
Zogenix IncCOM98978L2046,955281,797SHSOLE281,797 0 0