UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F COVER PAGE
OMB APPROVAL
OMB Number:3235-0006
Expires:July 31, 2015
Estimated average burden
hours per response:23.8
Report for the Calendar Year or Quarter Ended:
06-30-2023
Check here if Amendment: ☐ Amendment Number:
This Amendment (Check only one.):☐ is a restatement.
☐ adds new holdings entries.

Institutional Investment Manager Filing this Report:

Name:
Artal Group S.A.
Address:
VALLEY PARK
44, RUE DE LA VALLEE
LUXEMBOURG, N4 L-2661
Form 13F File Number:
028-15027

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.


Person Signing this Report on Behalf of Reporting Manager:
Name:
Anne Goffard
Title:
Authorized Person
Phone:
352224259-1


Signature, Place, and Date of Signing:

/s/ Anne Goffard
                         [Signature]
Luxembourg, LUXEMBOURG
                 [City, State]
08-11-2023
                           [Date]
                          

Report Type (Check only one.):

☒ 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.) 

☐ 13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).) 

☐ 13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)


Form 13F Summary Page

Report Summary:

Number of Other Included Managers:
5
Form 13F Information table Entry Total:
119
Form 13F Information table Value Total:
3226843
          (thousands)

List of Other Included Managers:

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.
[If there are no entries in this list, state "NONE" and omit the column headings and list entries.]

No.Form 13F File NumberNameCIK
1
028-15028
Stichting Administratiekantoor Westend
0001460840
2
028-15029
Westend S.A.
0001283968
3
028-15031
Artal International Management S.A.
0001522131
4
028-15033
Artal International S.C.A.
0001218180
5
028-11522
Invus Public Equities Advisors, LLC
0001340096


UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number:3235-0006
Expires:July 31, 2015
Estimated average burden
hours per response:23.8
COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
23ANDME HOLDING COCLASS A COM90138Q1081,157661,009SHDFND1,2,3,4,5661,009 0 0
ACELYRIN INCCOM00445A10038,0631,821,214SHDFND1,2,3,4,51,821,214 0 0
ACHILLES THERAPEUTICS PLCSPONSORED ADS00449L1022,1322,255,375SHDFND1,2,3,4,52,255,375 0 0
ADAGENE INCADS0053291071,4801,000,000SHDFND1,2,3,4,51,000,000 0 0
ADAPTIMMUNE THERAPEUTICS PLCSPONDS ADR00653A1071,0491,133,775SHDFND1,2,3,4,51,133,775 0 0
ADVANCED MICRO DEVICES INCCOM0079031076836,000SHDFND1,2,3,4,56,000 0 0
AGENUS INCCOM NEW00847G70525,01015,631,235SHDFND1,2,3,4,515,631,235 0 0
ALLOVIR INCCOM01981810322,4306,597,167SHDFND1,2,3,4,56,597,167 0 0
ALNYLAM PHARMACEUTICALS INCCOM02043Q107178936SHDFND1,2,3,4,5936 0 0
ALPHABET INCCAP STK CL A02079K3054794,000SHDFND1,2,3,4,54,000 0 0
ALPINE IMMUNE SCIENCES INCCOM02083G10012,2641,193,030SHDFND1,2,3,4,51,193,030 0 0
ALX ONCOLOGY HLDGS INCCOM00166B1053,755500,000SHDFND1,2,3,4,5500,000 0 0
AMAZON COM INCCOM0231351061,30410,000SHDFND1,2,3,4,510,000 0 0
AMBRX BIOPHARMA INCSPONSORED ADS02290A10211,560702,291SHDFND1,2,3,4,5702,291 0 0
AMICUS THERAPEUTICS INCCOM03152W10957,3064,562,567SHDFND1,2,3,4,54,562,567 0 0
AMICUS THERAPEUTICS INCCOM03152W1096,280500,000SHCallDFND1,2,3,4,5500,000 0 0
APELLIS PHARMACEUTICALS INCCOM03753U10695,6611,050,067SHDFND1,2,3,4,51,050,067 0 0
ARAVIVE INCCOM03890D1085,7614,572,515SHDFND1,2,3,4,54,572,515 0 0
ARROWHEAD PHARMACEUTICALS INCOM04280A1001945,440SHDFND1,2,3,4,55,440 0 0
AURINIA PHARMACEUTICALS INCCOM05156V1029,6801,000,000SHDFND1,2,3,4,51,000,000 0 0
AVIDITY BIOSCIENCES INCCOM05370A1083,327300,000SHDFND1,2,3,4,5300,000 0 0
BEAM THERAPEUTICS INCCOM07373V10535010,975SHDFND1,2,3,4,510,975 0 0
BEIGENE LTDSPONSORED ADR07725L10273,548412,496SHDFND1,2,3,4,5412,496 0 0
BIOMARIN PHARMACEUTICAL INCCOM09061G1014365,028SHDFND1,2,3,4,55,028 0 0
BLACK DIAMOND THERAPEUTICS ICOM09203E10510,3352,046,517SHDFND1,2,3,4,52,046,517 0 0
CARIBOU BIOSCIENCES INCCOM142038108448105,347SHDFND1,2,3,4,5105,347 0 0
CAVA GROUP INCCOM1489291021,310,72732,007,990SHDFND1,2,3,432,007,990 0 0
CEREVEL THERAPEUTICS HLDNG ICOM15678U12852,0991,638,858SHDFND1,2,3,4,51,638,858 0 0
CITIZENS FINL GROUP INCCOM17461010526110,000SHDFND1,2,3,4,510,000 0 0
CORVUS PHARMACEUTICALS INCCOM2210151001,145500,000SHDFND1,2,3,4,5500,000 0 0
CROWDSTRIKE HLDGS INCCL A22788C1055143,500SHDFND1,2,3,4,53,500 0 0
CULLINAN ONCOLOGY INCCOM2300311062,690250,000SHDFND1,2,3,4,5250,000 0 0
CURIS INCCOM NEW2312692001,0791,300,000SHDFND1,2,3,4,51,300,000 0 0
CYCLERION THERAPEUTICS INCCOM23255M204570138,403SHDFND1,2,3,4,5138,403 0 0
CYCLERION THERAPEUTICS INCCOM23255M1052552SHDFND1,2,3,4552 0 0
CYTOKINETICS INCCOM NEW23282W60546,1911,416,031SHDFND1,2,3,4,51,416,031 0 0
DANAHER CORPORATIONCOM23585110211,40047,500SHDFND1,2,3,4,547,500 0 0
DATADOG INCCL A COM23804L1034925,000SHDFND1,2,3,4,55,000 0 0
DAY ONE BIOPHARMACEUTICALS ICOM23954D1095,970500,000SHDFND1,2,3,4,5500,000 0 0
DENALI THERAPEUTICS INCCOM24823R10523,694802,899SHDFND1,2,3,4,5802,899 0 0
DYNE THERAPEUTICS INCCOM26818M1089,170815,085SHDFND1,2,3,4,5815,085 0 0
ERASCA INCCOM29479A10813,0304,721,194SHDFND1,2,3,4,54,721,194 0 0
FOGHORN THERAPEUTICS INCCOM34417410712,1141,720,720SHDFND1,2,3,4,51,720,720 0 0
FUSION PHARMACEUTICALS INCCOM36118A1008,0561,725,000SHDFND1,2,3,4,51,725,000 0 0
GENERATION BIO COCOM37148K10015,4782,814,191SHDFND1,2,3,4,52,814,191 0 0
GERON CORPCOM37416310317,8675,565,889SHDFND1,2,3,4,55,565,889 0 0
GLYCOMIMETICS INCCOM38000Q10214,9458,589,064SHDFND1,2,3,4,58,589,064 0 0
GOSSAMER BIO INCCOM38341P1023,6343,028,171SHDFND1,2,3,4,53,028,171 0 0
HARPOON THERAPEUTICS INCCOM41358P1067101,000,000SHDFND1,2,3,4,51,000,000 0 0
HIPPO HLDGS INCCOM NEW43353920239724,000SHDFND1,2,3,4,524,000 0 0
HOOKIPA PHARMA INCCOM43906K1004,9865,666,410SHDFND1,2,3,4,55,666,410 0 0
IGM BIOSCIENCES INCCOM44958510823,2802,522,244SHDFND1,2,3,4,54,209,744 0 0
IKENA ONCOLOGY INCCOM45175G10812,1331,849,513SHDFND1,2,3,4,51,849,513 0 0
I MABSPONSORED ADS44975P1032,542850,000SHDFND1,2,3,4,5850,000 0 0
IMMUNOGEN INCCOM45253H10114,445765,497SHDFND1,2,3,4,5765,497 0 0
INTELLIA THERAPEUTICS INCCOM45826J10511,258276,077SHDFND1,2,3,4,5276,077 0 0
IRONWOOD PHARMACEUTICALS INCCOM CL A46333X1081,176110,532SHDFND1,2,3,4110,532 0 0
ITEOS THERAPEUTICS INCCOM46565G1045,296400,000SHDFND1,2,3,4,5400,000 0 0
KANZHUN LIMITEDSPONSORED ADS48553T1063,311220,000SHDFND1,2,3,4,5220,000 0 0
KE HLDGS INCSPONSORED ADS4824971045,198350,000SHDFND1,2,3,4,5350,000 0 0
KINETA INCCOM49461C1028031,055SHDFND1,2,3,4,531,055 0 0
KINNATE BIOPHARMA INCCOM49705R105379125,000SHDFND1,2,3,4,5125,000 0 0
KRONOS BIO INCCOM50107A1042,6541,542,954SHDFND1,2,3,4,51,542,954 0 0
KRYSTAL BIOTECH INCCOM50114710241,051349,669SHDFND1,2,3,4,5349,669 0 0
KURA ONCOLOGY INCCOM50127T10921,3512,018,056SHDFND1,2,3,4,52,018,056 0 0
KYMERA THERAPEUTICS INCCOM50157510441,5051,805,346SHDFND1,2,3,4,51,805,346 0 0
LAVA THERAPEUTICS NVSHSN51517105406200,000SHDFND1,2,3,4,5200,000 0 0
LEXICON PHARMACEUTICALS INCCOM NEW5288723028,0523,516,214SHDFND1,2,3,4,53,516,214 0 0
LEXICON PHARMACEUTICALS INCCOM NEW528872302261,145114,037,070SHDFND1,2,3,4114,037,070 0 0
LUCID GROUP INCCOM5494981033,376490,000SHDFND1,2,3,4,5490,000 0 0
MERSANA THERAPEUTICS INCCOM59045L1069,9673,029,555SHDFND1,2,3,4,53,029,555 0 0
MICROSOFT CORPCOM5949181041,0223,000SHDFND1,2,3,4,53,000 0 0
MINK THERAPEUTICS INCCOM603693102479228,216SHDFND1,2,3,4,5228,216 0 0
MIRATI THERAPEUTICS INCCOM60468T10574,2542,055,181SHDFND1,2,3,4,52,055,181 0 0
MIRATI THERAPEUTICS INCCOM60468T1059,033250,000SHCallDFND1,2,3,4,5250,000 0 0
MOONLAKE IMMUNOTHERAPEUTICSCLASS A ORD61559X10420,400400,000SHDFND1,2,3,4,5400,000 0 0
MORPHIC HLDG INCCOM61775R105122,6862,139,995SHDFND1,2,3,4,52,139,995 0 0
MORPHIC HLDG INCCOM61775R1055,733100,000SHCallDFND1,2,3,4,5100,000 0 0
NANOBIOTIXSPONSORED ADS63009J1075,0701,000,000SHDFND1,2,3,4,51,000,000 0 0
NATERA INCCOM6323071049,732200,000SHDFND1,2,3,4,5200,000 0 0
OMEGA THERAPEUTICS INCCOM68217N10514,1852,533,045SHDFND1,2,3,4,52,533,045 0 0
OVID THERAPEUTICS INCCOM6904691018,2002,500,000SHDFND1,2,3,4,52,500,000 0 0
PLIANT THERAPEUTICS INCCOM729139105271,490SHDFND1,2,3,4,51,490 0 0
PORTAGE FINTECH ACQUISITN COCLASS A ORD SHSG7185D1063,941380,000SHDFND1,2,3,4,5380,000 0 0
PROCORE TECHNOLOGIES INCCOM74275K1082934,500SHDFND1,2,3,4,54,500 0 0
PROTAGONIST THERAPEUTICS INCCOM74366E10213,810500,000SHDFND1,2,3,4,5500,000 0 0
RELAY THERAPEUTICS INCCOM75943R10215,2441,213,725SHDFND1,2,3,4,51,213,725 0 0
REPARE THERAPEUTICS INCCOM7602731027,406700,000SHDFND1,2,3,4,5700,000 0 0
REPLIMUNE GROUP INCCOM76029N10611,610500,000SHDFND1,2,3,4,5500,000 0 0
REVOLUTION MEDICINES INCCOM76155X10064,2432,401,617SHDFND1,2,3,4,52,401,617 0 0
ROIVANT SCIENCES LTDSHSG7627910116,3801,625,000SHDFND1,2,3,4,51,625,000 0 0
SAGE THERAPEUTICS INCCOM78667J10823,510500,000SHDFND1,2,3,4,5500,000 0 0
SANA BIOTECHNOLOGY INCCOM7995661042,384400,000SHDFND1,2,3,4,5400,000 0 0
SCHOLAR ROCK HLDG CORPCOM80706P10368,3099,059,507SHDFND1,2,3,4,59,059,507 0 0
SCHRODINGER INCCOM80810D10334,944700,000SHDFND1,2,3,4,5700,000 0 0
SEA LTDSPONSORED ADS81141R10020,314350,000SHDFND1,2,3,4,5350,000 0 0
SEER INCCOM CL A81578P10620,2834,750,000SHDFND1,2,3,4,54,750,000 0 0
SELECTA BIOSCIENCES INCCOM81621210410,2339,136,635SHDFND1,2,3,4,59,136,635 0 0
SENTI BIOSCIENCES INCCOM81726A1003555,555SHDFND1,2,3,4,555,555 0 0
SILENCE THERAPEUTICS PLCADS82686Q1019,3501,700,000SHDFND1,2,3,4,51,700,000 0 0
SOLID BIOSCIENCES INCCOM NEW83422E2044,764909,219SHDFND1,2,3,4,5909,219 0 0
SPDR SER TRS&P BIOTECH78464A87083,2001,000,000SHCallDFND1,2,3,4,51,000,000 0 0
SPRINGWORKS THERAPEUTICS INCCOM85205L10747,6321,816,620SHDFND1,2,3,4,51,816,620 0 0
SQZ BIOTECHNOLOGIES COCOM78472W1044341,606,309SHDFND1,2,3,4,51,606,309 0 0
STERLING CHECK CORPCOM85917T10930725,000SHDFND1,2,3,4,525,000 0 0
STOKE THERAPEUTICS INCCOM86150R1072,658250,000SHDFND1,2,3,4,5250,000 0 0
SYROS PHARMACEUTICALS INCCOM NEW87184Q2064,6491,475,744SHDFND1,2,3,4,51,475,744 0 0
TAIWAN SEMICONDUCTOR MFG LTDSPONSORED ADS8740391004,28942,500SHDFND1,2,3,4,542,500 0 0
TALARIS THERAPEUTICS INCCOM87410C1042,779914,262SHDFND1,2,3,4,5914,262 0 0
TAYSHA GENE THERAPIES INCCOM SHS8776191069521,440,882SHDFND1,2,3,4,51,440,882 0 0
UNITED THERAPEUTICS CORP DELCOM91307C1026562,971SHDFND1,2,3,4,52,971 0 0
VENTYX BIOSCIENCES INCCOM92332V10713,399408,519SHDFND1,2,3,4,5408,519 0 0
VERVE THERAPEUTICS INCCOM92539P1015,625300,000SHDFND1,2,3,4,5300,000 0 0
VIGIL NEUROSCIENCE INCCOM92673K10817,9651,911,191SHDFND1,2,3,4,51,911,191 0 0
VIRIDIAN THERAPEUTICS INCCOM92790C10412,013504,978SHDFND1,2,3,4,5504,978 0 0
VISA INCCOM CL A92826C8391,7817,500SHDFND1,2,3,4,57,500 0 0
VOR BIOPHARMA INCCOM9290331088,3062,688,015SHDFND1,2,3,4,52,688,015 0 0
WAVE LIFE SCIENCES LTDSHSY9530810510,4492,870,523SHDFND1,2,3,4,52,870,523 0 0
XILIO THERAPEUTICS INCCOM98422T1001,179450,000SHDFND1,2,3,4,5450,000 0 0