UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F COVER PAGE
OMB APPROVAL
OMB Number:3235-0006
Expires:July 31, 2015
Estimated average burden
hours per response:23.8
Report for the Calendar Year or Quarter Ended:
12-31-2021
Check here if Amendment: ☐ Amendment Number:
This Amendment (Check only one.):☐ is a restatement.
☐ adds new holdings entries.

Institutional Investment Manager Filing this Report:

Name:
Logos Global Management LP
Address:
1 LETTERMAN DRIVE
STE. D3-700
San Francisco, CA 94129
Form 13F File Number:
028-20025

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.


Person Signing this Report on Behalf of Reporting Manager:
Name:
Virginia Yee
Title:
CFO/CCO
Phone:
415-801-4660


Signature, Place, and Date of Signing:

/s/ Virginia Yee
                         [Signature]
San Francisco, CALIFORNIA
                 [City, State]
02-14-2022
                           [Date]
                          

Report Type (Check only one.):

☒ 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.) 

☐ 13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).) 

☐ 13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)


Form 13F Summary Page

Report Summary:

Number of Other Included Managers:
0
Form 13F Information table Entry Total:
66
Form 13F Information table Value Total:
969614
          (thousands)

List of Other Included Managers:

Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.
[If there are no entries in this list, state "NONE" and omit the column headings and list entries.]

  
NONE


UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number:3235-0006
Expires:July 31, 2015
Estimated average burden
hours per response:23.8
COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ADAGIO THERAPEUTICS INCCOM00534A10250870,000SHSOLE70,000 0 0
ALIGOS THERAPEUTICS INCCOM01626L10536,9493,112,785SHSOLE3,112,785 0 0
ALNYLAM PHARMACEUTICALS INCCOM02043Q1075,93535,000SHSOLE35,000 0 0
ALPINE IMMUNE SCIENCES INCCOM02083G10015,5121,120,000SHSOLE1,120,000 0 0
ALX ONCOLOGY HLDGS INCCOM00166B10562,4582,906,352SHSOLE2,906,352 0 0
AMICUS THERAPEUTICS INCCOM03152W1097,219625,000SHSOLE625,000 0 0
APELLIS PHARMACEUTICALS INCCOM03753U10647,2801,000,000SHSOLE1,000,000 0 0
ARCUTIS BIOTHERAPEUTICS INCCOM03969K1085,185250,000SHSOLE250,000 0 0
ATHIRA PHARMA INCCOM04746L10421,2491,630,744SHSOLE1,630,744 0 0
BICYCLE THERAPEUTICS PLCSPONSORED ADS08878610852,957870,000SHSOLE870,000 0 0
BIOMEA FUSION INCCOM09077A1061,879252,320SHSOLE252,320 0 0
CENTESSA PHARMACEUTICALS PLCSPONSORED ADS1523091005,118454,545SHSOLE454,545 0 0
CENTURY THERAPEUTICS INCCOM15673T1009,739614,095SHSOLE614,095 0 0
COGENT BIOSCIENCES INCCOM19240Q2011,287150,000SHSOLE150,000 0 0
COMPASS PATHWAYS PLCSPONSORED ADS20451W1016,630300,000SHSOLE300,000 0 0
CULLINAN ONCOLOGY INCCOM2300311064,450288,458SHSOLE288,458 0 0
CYTOKINETICS INCCOM NEW23282W60560,3941,325,000SHSOLE1,325,000 0 0
DAY ONE BIOPHARMACEUTICALS ICOM23954D10962437,069SHSOLE37,069 0 0
DESIGN THERAPEUTICS INCCOM25056L10359,3592,772,501SHSOLE2,772,501 0 0
DICE THERAPEUTICS INCCOM23345J10442,1221,664,251SHSOLE1,664,251 0 0
DYNE THERAPEUTICS INCCOM26818M10838,4573,234,392SHSOLE3,234,392 0 0
EDGEWISE THERAPEUTICS INCCOM28036F10512,988850,000SHSOLE850,000 0 0
ELEDON PHARMACEUTICALS INCCOM28617K1015,9081,339,793SHSOLE1,339,793 0 0
ESSA PHARMA INCCOM NEW29668H70812,283865,000SHSOLE865,000 0 0
FATE THERAPEUTICS INCCOM31189P1025,50094,000SHSOLE94,000 0 0
FORMA THERAPEUTICS HLDGS INCSHS34633R10422,7521,600,000SHSOLE1,600,000 0 0
FULCRUM THERAPEUTICS INCCOM35961610912,118685,000SHSOLE685,000 0 0
GLOBAL BLOOD THERAPEUTICS INCOM37890U10821,953750,000SHSOLE750,000 0 0
GRAPHITE BIO INCCOM38870X1045,050406,308SHSOLE406,308 0 0
HARPOON THERAPEUTICS INCCOM41358P10614,5721,930,000SHSOLE1,930,000 0 0
IDEAYA BIOSCIENCES INCCOM45166A10236,6421,550,000SHSOLE1,550,000 0 0
IKENA ONCOLOGY INCCOM45175G1083,760299,853SHSOLE299,853 0 0
IVERIC BIO INCCOM46583P10221,7361,300,000SHSOLE1,300,000 0 0
JANUX THERAPEUTICS INCCOM47103J1053,653185,196SHSOLE185,196 0 0
JOUNCE THERAPEUTICS INCCOM48111610111,2731,350,000SHSOLE1,350,000 0 0
KARUNA THERAPEUTICS INCCOM48576A10039,300300,000SHSOLE300,000 0 0
KEZAR LIFE SCIENCES INCCOM49372L10024,2441,450,000SHSOLE1,450,000 0 0
KYMERA THERAPEUTICS INCCOM50157510412,698200,000SHSOLE200,000 0 0
LANDOS BIOPHARMA INCCOM5150691026,6001,375,000SHSOLE1,375,000 0 0
LIANBIOSPONSORED ADS53000N1082,543412,837SHSOLE412,837 0 0
MARINUS PHARMACEUTICALS INCCOM NEW56854Q2001,544130,000SHSOLE130,000 0 0
MEREO BIOPHARMA GROUP PLCADS5894921077546,984SHSOLE46,984 0 0
MIRATI THERAPEUTICS INCCOM60468T1057,33550,000SHSOLE50,000 0 0
NGM BIOPHARMACEUTICALS INCCOM62921N1058,412475,000SHSOLE475,000 0 0
NUVALENT INCCOM6707031072,563134,650SHSOLE134,650 0 0
NUVATION BIO INC*W EXP 07/07/20267080N11912666,666SHSOLE66,666 0 0
OLEMA PHARMACEUTICALS INCCOM68062P10635,0433,743,875SHSOLE3,743,875 0 0
OMEGA THERAPEUTICS INCCOMMON STOCK68217N10599988,235SHSOLE88,235 0 0
PROTAGONIST THERAPEUTICS INCCOM74366E1028,550250,000SHSOLE250,000 0 0
PYXIS ONCOLOGY INCCOMMON STOCK7473241013,144286,652SHSOLE286,652 0 0
RAIN THERAPEUTICS INCCOM75082Q1053,158245,161SHSOLE245,161 0 0
RELMADA THERAPEUTICS INCCOM75955J4029,012400,000SHSOLE400,000 0 0
REPARE THERAPEUTICS INCCOM76027310235,8531,700,000SHSOLE1,700,000 0 0
SOMALOGIC INCCLASS A COM83444K1052,333200,493SHSOLE200,493 0 0
SPRUCE BIOSCIENCES INCCOM85209E1094,9061,100,000SHSOLE1,100,000 0 0
TALARIS THERAPEUTICS INCCOM87410C1045,031329,013SHSOLE329,013 0 0
TRAVERE THERAPEUTICS INCCOM89422G1073,104100,000SHSOLE100,000 0 0
TYRA BIOSCIENCES INCCOM90240B1066,660473,394SHSOLE473,394 0 0
VENTYX BIOSCIENCES INCCOM92332V10736,2301,824,280SHSOLE1,824,280 0 0
VERA THERAPEUTICS INCCL A92337R1011,33650,000SHSOLE50,000 0 0
VERONA PHARMA PLCSPONSORED ADS925050106820122,000SHSOLE122,000 0 0
VERVE THERAPEUTICS INCCOM92539P10116,343443,265SHSOLE443,265 0 0
VISTAGEN THERAPEUTICS INCCOM NEW92840H2023,9002,000,000SHSOLE2,000,000 0 0
WAVE LIFE SCIENCES LTDSHSY953081052,512800,000SHSOLE800,000 0 0
Y-MABS THERAPEUTICS INCCOM9842411094,053250,000SHSOLE250,000 0 0
ZOGENIX INCCOM NEW98978L2045,688350,000SHSOLE350,000 0 0